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BIOCREDIT Malaria Ag Pf (pLDH/HRPⅡ)

One Step Malaria Ag Pf (pLDH/HRPⅡ) Test

BIOCREDIT Malaria Ag Pf (pLDH/HRPⅡ) can detect not only HRPⅡ but also pLDH prevailing over false negative issues that have been reported due to HRPⅡ gene deletion issues since 2015. The Plasmodium Lactate Dehydrogenase (pLDH) is an oxidoreductase. It is the last enzyme of the glycolytic pathway, essential for ATP generation, and one of the most abundant enzymes expressed by P.falciparum. pLDH does not persist in the blood but clears about the same time as the parasites following successful treatment. The lack of antigen persistence after treatment makes the pLDH from P.vivax, P.ovale, or P.malariae exhibit 90-92% identity to pLDH from P.falciparum. HRPⅡ is expressed only by P.falciparum. Therefore test result will be expressed as negative (some P.falciparum strains also don’t have HRPⅡ). The variability in the results of HRPⅡ-based RDTs is related to the variability in the target antigen.

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  • I Specification

    Intended use Detection of pLDH and HRPⅡ from P.falciparum
    Storage 1-40℃ / 33.8-104℉
    Specimen type Whole blood
    Specimen volume 5㎕
    Time to result 25-35 minutes
    Shelf life 24 months
    Sensitivity pLDH : 93.72%, HRPⅡ: 98.33%
    Specificity pLDH : 100.0%, HRPⅡ: 100.0%

  • I Video

  • I Components

    - BIOCREDIT Malaria Ag Pf (pLDH/HRPⅡ) Test device

    - Assay buffer bottle

    - Disposable capillary pipette (or inverted cup) 

    - Lancet and alcohol swab (C13RHG25 only)

    - Lancet, alcohol swab and glove (C13RHH25 only)

    - Instruction for use

  • I Procedure



     

  • I Interpretation



     

  • I Ordering Information

    Cat No. Product Type Package size Specimen
    C13RHA25 Malaria Ag Pf (pLDH/HRPⅡ)
    Device 1Tx25/Kit WB
    C13RHG25 Malaria Ag Pf (pLDH/HRPⅡ)
    Device 1Tx25/Kit WB
    C13RHH25 Malaria Ag Pf (pLDH/HRPⅡ)
    Device 1Tx25/Kit WB